محتوى المقال

Namrata Dhadnekar Kapil Kumar Devanshi Bhatt Himali Upadhyay Shibu Pillai Uma Harikrishnan

الملخص

يتم إعطاء مرضى الفصام في جميع أنحاء العالم بشكل روتيني أدوية مضادة للذهان. من أجل اكتشاف حالات مثل: جرعة زائدة من المخدرات أو تعاطي المخدرات، أو التسمم المتعمد، وهناك حاجة إلى مجسات بسيطة وانتقائية وحساسة. في هذا العمل، قمنا بتصنيع مجس فلورسنتي (CRSA) وتمييزه بواسطة FT-IR و NMR وقياس الطيف الكتلي. يصدر المجس ضوءًا أخضر في الإيثان ويعمل كمستشعر إطفاء للضوء للعقار المضاد للذهان أميسولبريد (AMI) بنسبة إطفاء تبلغ 94 ٪ وحدًا ممتازًا للكشف يبلغ 1.6 ميكرومتر. استجاب المستشعر بشكل فعال فقط لـ AMI حتى في وجود أدوية أخرى مثل: سيرترالين، وفلوكستين، وإسكيتالوبرام، وبروكسيتين، وأولانزابين، وكلوزابين، مما يضمن تحديدًا وانتقائية جيدة لهذه الطريقة. كما تمت دراسة تأثير الأس الهيدروجيني على قدرات الاستشعار لـ CRSA وإمكانية تطبيق الطريقة على عينات واقعية باستخدام عينات كحولية تم إضافتها له

التنزيلات

تنزيل البيانات ليس متاحًا بعد.

المراجع

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الأوراق البحثية الأصيلة (الإبداعية)
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