Vertical fragmentation technique is used to enhance the performance of database system and reduce the number of access to irrelevant instances by splitting a table or relation into different fragments vertically. The partitioning design can be derived using FPClose algorithm, which is a data mining algorithm used to extract the frequent closed itemsets in a dataset. A new design approach is implemented to perform fragmentation. A benchmark with different minimum support levels is tested. The obtained results from FPClose algorithm are compared with the Apriori algorithm.